منابع مشابه
Fructose Intolerance and Hypoglucosemia in the Newborn Fructose Tolerance
The normal newborn infant has inadequate homeostatic mechanisms for stabilizing the concentration of glucose in the blood (1, 2). Recent studies of carbohydrate metabolism in this age group have indicated a diminished responsiveness to small doses (30 jug per kg body weight) of exogenous glucagon (3, 4) and a slow rate of disappearance from the blood of either glucose or galactose administered ...
متن کاملFructose, Glucose, and Galactose Tolerance in Dogs
In a recent study, Folin and Berglund (1) describe certain phenomena associated with the transportation, retention, and excretion of carbohydrates. Data are presented to show that both fructose and galactose are less effective than glucose in raising the level of the blood sugar. The explanation offered is that the tissues, being relatively well stored with glucose and empty of other sugars may...
متن کاملIntestinal, but not hepatic, ChREBP is required for fructose tolerance.
Increased sugar consumption is a risk factor for the metabolic syndrome including obesity, hypertriglyceridemia, insulin resistance, diabetes, and nonalcoholic fatty liver disease (NAFLD). Carbohydrate responsive element-binding protein (ChREBP) is a transcription factor that responds to sugar consumption to regulate adaptive metabolic programs. Hepatic ChREBP is particularly responsive to fruc...
متن کاملRole of AMPD2 in impaired glucose tolerance induced by high fructose diet
A high intake of products containing fructose is known to mediate insulin resistance. In the liver, AMPD2, an isoform of AMPD, has important glucose metabolic homeostasis functions including maintenance of AMP-activated protein kinase (AMPK). We speculated that AMPD2 induces impaired glucose tolerance in individuals who consume a high-fructose diet. We gave either a normal-chow (NCD) or high-fr...
متن کاملIncreased skeletal muscle mitochondrial efficiency in rats with fructose-induced alteration in glucose tolerance.
In the present study, the effect of long-term fructose feeding on skeletal muscle mitochondrial energetics was investigated. Measurements in isolated tissue were coupled with the determination of whole-body energy expenditure and insulin sensitivity. A significant increase in plasma NEFA, as well as in skeletal muscle TAG and ceramide, was found in fructose-fed rats compared with the controls, ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1967
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5572.138